Neurons are elastic…

Following a pathology or a trauma, the regeneration of the central and peripheral nervous system is today a major societal issue in the context of an aging population. This plasticity, driven by the growth and differentiation of cells into neurons, for example, depends on a large number of parameters.
The correlation between these repair mechanisms and the elastic response of the environment or the cells is often mentioned but remains difficult to quantify. Nevertheless, researchers from the INSP in collaboration with the LCMCP and SPPIN have taken a crucial step towards this objective by quantifying, at the micrometric scale, the elastic inhomogeneities into single neuron.


Caption: Cell mapping according to the fitted frequencyfB(GHz). Blue dots:11.9<fB<12.911.9<fB<12.9. Red dots: 9.0<fB<11.99.0<fB<11.9. Green dots: fB<9.0fB<9.0.

“Picosecond ultrasounds as elasticity probes in neuron-like cells models”
A. Viel, E. Peronne, O. Sénépart, L. Becerra, C. Legay, F. Semprez, L. Trichet, T. Coradin, A. Hamraoui, L. Belliard
APPLIED PHYSICS LETTERS Volume : 115 Issue : 21 Article Number : 213701 DOI : 10.1063/1.5129783


Laurent Belliard : laurent.belliard[at]